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9 Drugs Linked To Alzheimer’s Disease

Bring Down Blood Pressure Now

Breakthrough drug slows down Alzheimers disease | 9 News Australia

While more research investigates the brain benefits of blood pressure meds, you can play it smart by taking healthy lifestyle steps to keep blood pressure in a healthy range. Here are some of the best strategies.

Eat real.

That means nixing processed foodseven canned vegetables, which are oftenhigh in sodium. Among the most successful blood-pressure-lowering diets area Mediterranean diet or DASH .Both diets are high in fruits, vegetables,whole grains, low-fat dairy, poultry, fish and nuts, but low in harmful fats, red meat,sweets and sugary drinks. The effects can be quick, with blood pressurereductions in just two weeks.

Shed extra weight.

In one analysis of 25 clinical trials, losing an average of 11 poundsshaved 4.4 points offsystolic blood pressure and 3.6 points offdiastolic. Other studies have found that modest weight loss canprevent hypertension in overweight people, even if they dont reduce theamount of sodium in their diet.

Check blood pressure at home.

Monitoring your blood pressure at home can improve blood pressuremanagement more than just seeing your doctor. You can purchase automaticblood pressure cuffs for as little as $35 ask your doctor for arecommendation. Many pharmacies and drugstores also offer free bloodpressure readings.

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What Are The Symptoms Of Dementia

Early symptoms of dementia include:

  • Forgetting recent events or information.
  • Repeating comments or questions over a very short period.
  • Misplacing commonly used items or placing them in unusual spots.
  • Not knowing the season, year or month.
  • Having difficulty coming up with the right words.
  • Experiencing a change in mood, behavior or interests.

Signs that dementia is getting worse include:

  • Your ability to remember and make decisions further declines.
  • Talking and finding the right words becomes more difficult.
  • Daily complex tasks, such as brushing your teeth, making a cup of coffee, working a TV remote, cooking and paying bills become more challenging.
  • Lessening of rational thinking and behavior and your ability to problem-solve.
  • Sleeping pattern changes.
  • Increases or worsening of anxiety, frustration, confusion, agitation, suspiciousness, sadness and/or depression.
  • Needing more help with activities of daily living, such as grooming, toileting, bathing and eating.
  • Experiencing hallucinations .

These symptoms are general symptoms of dementia. Each person diagnosed with dementia has different symptoms, depending on what area of their brain is damaged. Additional symptoms and/or unique symptoms occur with specific types of dementia.

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Does Big Pharma Have Any Interest In Curing The Disease No Way

With sales around $5 billion now, and a forecast to DOUBLE that number to $10.4 billion by 2021

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Finding The Cause Of Memory Loss

Alzheimer

If you find that you are increasingly forgetful or if memory problems interfere with your daily life, schedule an appointment with your doctor to determine the cause and best treatment.

To evaluate memory loss, your doctor will take a medical history, perform a physical exam — including a neurologic exam — and ask questions to test mental ability. Depending on the results, further evaluation may include blood and urine tests, nerve tests, and imaging tests of the brain such as computerized axial tomography scans or magnetic resonance imaging .

You may also be sent for neuropsychological testing, which is a battery of tests that help pinpoint the memory loss.

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What Should You Do If You Take These Drugs

Keep in mind that the research shows associations and correlationsnot causation or definitive proof.

However, if you are an older person or have Alzheimers risk factors, its a good idea to talk with your doctor about your medications. Are there non-anticholinergic medications you can take instead? Do the benefits of your medication outweigh its risks? Perhaps you can revisit beneficial lifestyle habits to help control your symptoms.

Another question to ask is if you are taking the lowest possible effective dose. The researchers at the University of California in San Diego found that the older people in the study were taking much higher doses of anticholinergic drugs than recommended for their ages. The majority were taking double the recommended dosage and 18% were taking four times the optimal dose. One first step might be to find out if you are taking too high a dose another would be to see how many anticholinergic drugs you are taking to see your total intake.

A doctor in England has created an online tool, the Anticholinergic burden calculator, where you can plug in what drugs you are taking and see how they combine. If you have a score of three or higher on this calculator, you are considered at higher risk of developing cognitive impairment.

Antidepressants And Mood Modulators

Antidepressants have an important role in the treatment of mood disorders in patients with AD. Depression is observed in more than 30% of patients with AD, and it frequently begins before AD is clinically diagnosed. Therefore, palliation of this frequent comorbid condition may improve cognitive and noncognitive performance.

Nyth found citalopram to be beneficial in mood and other neuropsychiatric symptoms in patients in the moderate stage of AD. Because citalopram can cause dose-dependent increases in the QT interval, the FDA recommends using a maximum of 40 mg a day and considering 20 mg a day in the elderly.

In a randomized, placebo-controlled study in 186 patients with probable AD and clinically significant agitation, treatment with 30 mg of citalopram daily reduced agitation and caregiver distress. However, citalopram also increased the risk of adverse cardiac events and slightly reduced cognition, which the study authors note may limit its practical application. In addition, while the study was being conducted the FDA issued an advisory warning that citalopram can prolong the QT interval and older patients should not use doses greater than 20 mg.

Weintraub et al and Petracca et al found sertraline and fluoxetine to have no short- or long-term benefit in mood over placebo. Similarly, Banerjee et al found that treatment of depression with sertraline or mirtazapine provided no benefit compared with placebo and increased the risk of adverse events.

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Yes Study After Study Shows Finallywe Have A Natural Safe Way To Help Us Fight Cancer

But Sour Honey isnt just some lab experiment either

In fact, the lucky folks who have already discovered it are reporting near-miraculous results…

Like this case study report from Dr. Osamu Mizukami and his patient Bill G.

Bill was a 49-year-old man suffering from stage III stomach cancer and desperate to live long enough see his only daughter graduate from college.

He had a surgery scheduled to remove the deadly tumors in his stomach, butterrified of going under the knifehe agreed to meet with Dr. Mizukami and try one last treatment.

Dr. Mizukami immediately put Bill on the Sour Honey protocol, then sent him home.

When Bill went back to meet with his surgeon a few months later they were BOTH shocked to find this miracle

Every single cancer cell had disappeared… GONE.

There was no trace of cancer left in his body.

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That was 7 long years ago, and he is still healthy today all thanks to the Sour Honey that saved his life.

This kind of result is so rare in the world of cancer treatment

Treatment Of Secondary Symptoms

US approves first new Alzheimer’s drug in 20 years – BBC News

A variety of behavioral and pharmacologic interventions can alleviate clinical manifestations of AD, such as anxiety, agitation, depression, psychotic behavior, and sleep problems. The effectiveness of such interventions ranges from modest and temporary to excellent and prolonged. No specific agent or dose of individual agents is unanimously accepted for the wide array of clinical manifestations. At present, the FDA has not approved any psychotropic agent for the treatment of AD.

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So While Its Still Available Right Now

Were just moments away from revealing the #1 secret treatment AND giving you full access to your complimentary copy of The Insiders Book of Secrets.

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Im about to reveal a hidden symptom that HALF of all seniors havebut dont know itthat could send them straight into a fatal heart attack

Forget everything youve heard about heart attacks and how to avoid them heres the story no-one is talking about.

And heres the scariest part even if youre the healthiest person you know eating all the right foods, exercising daily, keeping your blood pressure and cholesterol in check

You could still be a PRIME TARGET for this lethal disease.

And by the time you start to actually feel the symptomsunfortunately youre already too late.

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Why? You guessed it COLD. HARD. CASH.

It makes sense for them they have hundreds of drugs to treat all of those heart health issues.

And those hundreds of drugs are shilled to the tune of $64.4 BILLION, in fact.

Except every single one doesnt do jack for one of the potential causes of fatal heart attacks

What is it? To put it simply scientists arent exactly sure why this happens to some and not others, but it has to do with the way your body processes calcium.

Two Common Classes Of Drugs Have Been Linked To Dementia Fortunately There Are Alternatives To Both

Image: Thinkstock

If you’re worried about developing dementia, you’ve probably memorized the list of things you should do to minimize your riskeating a healthy diet, exercising regularly, getting adequate sleep, and keeping your mind and soul engaged. In addition, some of the drugs you may be taking to help you accomplish those things could increase your risk of dementia. In two separate large population studies, both benzodiazepines and anticholinergics were associated with an increased risk of dementia in people who used them for longer than a few months. In both cases, the effect increased with the dose of the drug and the duration of use.

These findings didn’t come entirely as a surprise to doctors who treat older people. The Beer’s List published by the American Geriatrics Society has long recognized benzodiazepines, antihistamines, and tricyclic antidepressants as potentially inappropriate for older adults, given their side effects. Such drugs are on the list because they share troubling side effectsconfusion, clouded thinking, and memory lapsesthat can lead to falls, fractures, and auto accidents.

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What Can I Expect If I Have Dementia

Stop Aging Now: 9 drugs linked to Alzheimer

Getting a diagnosis of dementia is certainly difficult to hear. Several types of dementia arent reversible. Others are a side effect of other serious diseases. Some dementia-like symptoms are due to conditions that can be treated and reversed.

Your healthcare team, which will probably include a neurologist and/or a geriatric-psychiatrist or a geriatrician, will order the needed tests to make the correct diagnosis. The medications available today focus on slowing the decline.

The goal is to maintain your or your loved ones quality of life. Some people with Alzheimers dementia can live up to two decades, but each person has their own unique course. Researchers continue learning about the mechanisms that cause dementia and testing different methods to slow, and someday, hopefully, cure this disease.

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An Almost 50% Increase In Risk

For their study, lead researcher Prof. Carol Coupland and team analyzed the medical records of 58,769 people with dementia and 225,574 people without dementia. They were all 55 years old or above at baseline.

Among those with dementia, 63% were women and the average age was 82. For each person with dementia, the researchers found five control matches of the same age and sex and who attended the same general practice to receive medical care.

Prof. Coupland and colleagues sourced the data from the QResearch database and looked at medical records from between January 1, 2004 and January 31, 2016.

The researchers found that anticholinergic drugs in general were associated with a higher risk of dementia. More specifically, however, anticholinergic antidepressants, antipsychotic drugs, anti-Parkinsons drugs, bladder drugs, and epilepsy drugs were associated with the highest increase in risk.

Among these, the most frequently prescribed drugs were antidepressants, anti-vertigo drugs, and bladder antimuscarinic drugs .

These results remained even after the researchers controlled for confounding variables , including body mass index , smoking status, alcohol use, cardiovascular problems, and the use of other medication, such as antihypertensive drugs.

This study provides further evidence that doctors should be careful when prescribing certain drugs that have anticholinergic properties, explains study co-author Prof. Tom Dening.

What Prescription Drugs Are Linked To Memory Loss

Both over-the-counter and prescription drugs can cause memory problems as side effects. Some medications have been linked to Alzheimers and other dementias. We’ll describe some commonly prescribed medications that can affect memory or cause memory loss in the following paragraphs.

Benzodiazepines

Benzodiazepines are anti-anxiety drugs used to treat anxiety, insomnia, delirium, agitation, and muscle spasms. Examples include diazepam , alprazolam , clonazepam , chlordiazepoxide , lorazepam , and temazepam .

Benzodiazepines slow down activity in the central nervous system, including areas of the brain involved with the transfer of short-term memory to long-term memory. Benzodiazepines are prescribed to older adults with caution because they stay in their systems longer due to their reduced kidney and liver function. A buildup of benzodiazepines can lead to memory loss, delirium, and other cognitive issues.

Anticholinergic Medications

Sleeping Pills

Non-benzodiazepine sedative-hypnotics are a drug class used to treat insomnia, commonly referred to as sleeping pills. Examples include zolpidem , zaleplon , and eszopiclone .

Although sleeping pills are not the same as benzodiazepines, they affect some of the same brain chemical messengers and nerve pathways in the central nervous system. Sleeping pills can cause amnesia and severe psychiatric side effects such as behavioral change, sleep disturbance, and depression.

Statins

Antiseizure Drugs

Narcotic Painkillers

Dopamine Agonists

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Which Medications Are Anticholinergics

You might be surprised to know that anticholinergic medications include seemingly harmless over-the-counter medications like antihistamines and sleep aids .

To help you understand which prescription and over-the-counter drugs have anticholinergic effects, we found a helpful list from ElderConsult Geriatric Medicine of common medical conditions and the anticholinergic medications typically used to treat them.

Medical conditions include a wide variety of common issues like overactive bladder, sleep issues, coughs, colds, allergies, behavior issues, mood disorders, chronic obstructive pulmonary disease , and Parkinsons disease.

This list might not include every single condition or medication, but its a good start to finding out if any of your older adults medications are anticholinergics.

Use this list to have an informed conversation with your older adults doctor about the risks and benefits of taking that medication.

These side effects can make existing dementia symptoms worse or make someone without cognitive issues behave as if they have Alzheimers or dementia.

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