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How Is The Body Affected By Alzheimer’s

Alzheimers Patients And Heart Health

What is Alzheimer’s disease?

Those with loved ones suffering from Alzheimers should keep the signs of a heart attack in mind. These include chest pain, pain that spreads to the arm, dizziness or nausea, pain in the throat or jaw, and an irregular heartbeat. Not all heart conditions have easily noticeable symptoms like a heart attack, however, which is why it is imperative to see a cardiologist regularly to monitor blood pressure, atherosclerosis and other signs of heart disease. Like Alzheimers, heart conditions are known to worsen over time, and early intervention is key to prevention.

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Isnt Dementia Part Of Normal Aging

No, many older adults live their entire lives without developing dementia. Normal aging may include weakening muscles and bones, stiffening of arteries and vessels, and some age-related memory changes that may show as:

  • Occasionally misplacing car keys
  • Struggling to find a word but remembering it later
  • Forgetting the name of an acquaintance
  • Forgetting the most recent events

Normally, knowledge and experiences built over years, old memories, and language would stay intact.

Impact On Families And Carers

In 2019, informal carers spent on average 5 hours per day providing care for people living with dementia. This can be overwhelming . Physical, emotional and financial pressures can cause great stress to families and carers, and support is required from the health, social, financial and legal systems. Fifty percent of the global cost of dementia is attributed to informal care.

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How Does Alzheimers Affect The Body And How Does Memory Care Help

Chances are youre familiar with the devastating symptoms of Alzheimers disease and how it affects your brain.

Its also very common. Alzheimers disease affects more than 5 million Americans who are over the age of 65, according to the Johns Hopkins School of Medicine.

Its statistics like this that demonstrate how important it is to provide special activities and exercises in memory care.

While most Americans are aware of the memory issues and impaired thinking that come with Alzheimers, are you aware that it can affect other systems in your body?

Well take a look at these effects and how assisted living with memory care in Wilmington can help your loved one who may be experiencing these symptoms.

Medications For Cognitive Symptoms

How Alzheimers Affects The Brain &  The Body (The SCARY ...

No disease-modifying drugs are available for Alzheimers disease, but some options may reduce the symptoms and help improve quality of life.

Drugs called cholinesterase inhibitors can ease cognitive symptoms, including memory loss, confusion, altered thought processes, and judgment problems. They improve neural communication across the brain and slow the progress of these symptoms.

Three common drugs with Food and Drug Administration approval to treat these symptoms of Alzheimers disease are:

  • donepezil , to treat all stages
  • galantamine , to treat mild-to-moderate stages
  • rivastigmine , to treat mild-to-moderate stages

Another drug, called memantine , has approval to treat moderate-to-severe Alzheimers disease. A combination of memantine and donepezil is also available.

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What Happens To The Brain In Alzheimer’s Disease

The healthy human brain contains tens of billions of neuronsspecialized cells that process and transmit information via electrical and chemical signals. They send messages between different parts of the brain, and from the brain to the muscles and organs of the body. Alzheimers disease disrupts this communication among neurons, resulting in loss of function and cell death.

Managing Alzheimer’s Disease Behavior

Common behavioral symptoms of Alzheimers include sleeplessness, wandering, agitation, anxiety, and aggression. Scientists are learning why these symptoms occur and are studying new treatments drug and nondrug to manage them. Research has shown that treating behavioral symptoms can make people with Alzheimers more comfortable and makes things easier for caregivers.

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Icipating In Alzheimer’s Disease Clinical Trials

Everybody those with Alzheimers disease or MCI as well as healthy volunteers with or without a family history of Alzheimers may be able to take part in clinical trials and studies. Participants in Alzheimers clinical research help scientists learn how the brain changes in healthy aging and in Alzheimers. Currently, at least 270,000 volunteers are needed to participate in more than 250 active clinical trials and studies that are testing ways to understand, diagnose, treat, and prevent Alzheimers disease.

Volunteering for a clinical trial is one way to help in the fight against Alzheimers. Studies need participants of different ages, sexes, races, and ethnicities to ensure that results are meaningful for many people. To learn more about clinical trials, watch this video from NIH’s National Library of Medicine.

NIA leads the federal governments research efforts on Alzheimers. NIA-supported Alzheimers Disease Research Centers throughout the U.S. conduct a wide range of research, including studies of the causes, diagnosis, and management of the disease. NIA also sponsors the Alzheimers Clinical Trials Consortium, which is designed to accelerate and expand studies and therapies in Alzheimers and related dementias.

To learn more about Alzheimers clinical trials and studies:

  • Talk to your health care provider about local studies that may be right for you.

Watch videos of participants in Alzheimers disease clinical trials talking about their experiences.

How Does A Memory Care Unit Help Those With Alzheimers

What Does Alzheimers Do to the Human Brain?

We understand the devastating toll Alzheimers takes on families. Thats one reason why we have 28 beds dedicated to our residents who have memory care issues.

These beds are part of our Memory Care Unit. . In this unit, our residents receive care from friendly employees who have been specifically trained to provide a secure, yet stimulating environment.

We dont just provide care for those with Alzheimerswe provide care for all of those with all forms of dementia.

Want to know more? Schedule a virtual tour with us. But hurry, our spaces are limited.

We look forward to hearing from you.

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How The Body Shuts Down

As your body declines it raises the risk for other health problems.

  • Infections may develop as your immune system begins to fail.
  • Pneumonia can set in, especially if you inhale food or drinks by accident.
  • Injuries from falls are more likely to happen.

Most people with Alzheimer’s disease die from pneumonia, another infection, or a heart attack.

It’s best to have conversations early on about how you’d like to be cared for. These conversations can be hard, but having a plan can make it easier for you and your family.

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Disproportionate Impact On Women

Globally, dementia has a disproportionate impact on women. Sixty-five percent of total deaths due to dementia are women, and disability-adjusted life years due to dementia are roughly 60% higher in women than in men. Additionally, women provide the majority of informal care for people living with dementia, accounting for 70% of carer hours.

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How Does Alzheimers Affect The Digestive System

Researchers have found a connection between the microorganisms in our gastrointestinal system to a variety of health conditions including Alzheimers disease. The intestinal flora can produce something called amyloid, which enters the blood circulation and crosses the blood-brain barrier to get into the brain.

The accumulation of amyloid plaques between nerve cells in the brain is one of the hallmarks of Alzheimers disease. There is also a component of bacterial cell membranes known as lipopolysaccharides that can get into the bodys bloodstream and activate inflammatory processes which contribute to Alzheimers.

The risk can be reduced by eating a plant-based diet rich in fruit and vegetables and high in fiber. The Mediterranean Diet is a popular one that has been shown to reduce Alzheimers disease risk. Black and green tea can also help support gut health.

Loss Of Neuronal Connections And Cell Death

Difference Between Alzheimer

In Alzheimers disease, as neurons are injured and die throughout the brain, connections between networks of neurons may break down, and many brain regions begin to shrink. By the final stages of Alzheimers, this processcalled brain atrophyis widespread, causing significant loss of brain volume.

Learn more about Alzheimer’s disease from MedlinePlus.

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Physical Changes To Expect

Which symptoms you have and when they appear are different for everyone.

Some people have physical problems before serious memory loss.

In one study, people who walked slowly and had poor balance were more likely to be diagnosed with Alzheimer’s disease in the following 6 years.

Some of the changes you might experience are:

  • Loss of balance or coordination
  • Stiff muscles
  • Seizures and uncontrollable twitches

When Someone You Love Has Alzheimer Disease

You might feel sad or angry or both if someone you love has Alzheimer disease. You might feel nervous around the person, especially if he or she is having trouble remembering important things or can no longer take care of himself or herself.

You might not want to go visit the person, even though your mom or dad wants you to. You are definitely not alone in these feelings. Try talking with a parent or another trusted adult. Just saying what’s on your mind might help you feel better. You also may learn that the adults in your life are having struggles of their own with the situation.

If you visit a loved one who has Alzheimer disease, try to be patient. He or she may have good days and bad days. It can be sad if you can’t have fun in the same ways together. Maybe you and your grandmother liked to go to concerts. If that’s no longer possible, maybe bring her some wonderful music and listen together. It’s a way to show her that you care and showing that love is important, even if her memory is failing.

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What Are The Most Common Types Of Dementia

  • Alzheimers disease. This is the most common cause of dementia, accounting for 60 to 80 percent of cases. It is caused by specific changes in the brain. The trademark symptom is trouble remembering recent events, such as a conversation that occurred minutes or hours ago, while difficulty remembering more distant memories occurs later in the disease. Other concerns like difficulty with walking or talking or personality changes also come later. Family history is the most important risk factor. Having a first-degree relative with Alzheimers disease increases the risk of developing it by 10 to 30 percent.
  • Vascular dementia. About 10 percent of dementia cases are linked to strokes or other issues with blood flow to the brain. Diabetes, high blood pressure and high cholesterol are also risk factors. Symptoms vary depending on the area and size of the brain impacted. The disease progresses in a step-wise fashion, meaning symptoms will suddenly get worse as the individual gets more strokes or mini-strokes.
  • Lewy body dementia. In addition to more typical symptoms like memory loss, people with this form of dementia may have movement or balance problems like stiffness or trembling. Many people also experience changes in alertness including daytime sleepiness, confusion or staring spells. They may also have trouble sleeping at night or may experience visual hallucinations .

What Is Stage 4 Alzheimers Disease

How does the brain work?

Stage 4 lasts for about 2 years and marks the onset of diagnosable Alzheimers disease. You and your loved ones will have more problems in their daily work, albeit complicated. Mood changes such as withdrawal and refusal are more pronounced. Emotional responsiveness also often declines, especially in difficult situations.

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How Is The Body Affected By Alzheimer’s/pathology

  • Harmful proteins build up in the brain, and causes what is called plaques and tangles
  • Plaques are deposits of proteins, while tangles are twisted proteins
  • These interfere with regular brain function by killing and deteriorating brain cells
  • They appear in normal aging as well, but in Alzheimers there are significantly more and affects the parts of the brain in a pattern
  • They first invade the part of the brain responsible for memory, the hippocampus, then spreads to other areas
  • Scientist speculate that they block communication between nerve cells in the brain, which causes them to die
  • Alzheimers Disease Vs Other Types Of Dementia

    Dementia is an umbrella term for a range of conditions that involve a loss of cognitive functioning.

    Alzheimers disease is the most common type of dementia. It involves plaques and tangles forming in the brain. Symptoms start gradually and are most likely to include a decline in cognitive function and language ability.

    To receive a diagnosis of Alzheimers, a person will be experiencing memory loss, cognitive decline, or behavioral changes that are affecting their ability to function in their daily life.

    Friends and family may notice the symptoms of dementia before the person themselves.

    There is no single test for Alzheimers disease. If a doctor suspects the presence of the condition, they will ask the person and sometimes their family or caregivers about their symptoms, experiences, and medical history.

    The doctor may also carry out the following tests:

    • cognitive and memory tests, to assess the persons ability to think and remember
    • neurological function tests, to test their balance, senses, and reflexes
    • blood or urine tests
    • a CT scan or MRI scan of the brain
    • genetic testing

    A number of assessment tools are available to assess cognitive function.

    In some cases, genetic testing may be appropriate, as the symptoms of dementia can be related to an inherited condition such as Huntingtons disease.

    Some forms of the APOE e4 gene are associated with a higher chance of developing Alzheimers disease.

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    What Increases The Risk For Dementia

    • AgeThe strongest known risk factor for dementia is increasing age, with most cases affecting those of 65 years and older
    • Family historyThose who have parents or siblings with dementia are more likely to develop dementia themselves.
    • Race/ethnicityOlder African Americans are twice more likely to have dementia than whites. Hispanics 1.5 times more likely to have dementia than whites.
    • Poor heart healthHigh blood pressure, high cholesterol, and smoking increase the risk of dementia if not treated properly.
    • Traumatic brain injuryHead injuries can increase the risk of dementia, especially if they are severe or occur repeatedly.

    Vascular Contributions To Alzheimers Disease

    Impact of Alzheimer

    People with dementia seldom have only Alzheimers-related changes in their brains. Any number of vascular issuesproblems that affect blood vessels, such as beta-amyloid deposits in brain arteries, atherosclerosis , and mini-strokesmay also be at play.

    Vascular problems may lead to reduced blood flow and oxygen to the brain, as well as a breakdown of the blood-brain barrier, which usually protects the brain from harmful agents while allowing in glucose and other necessary factors. In a person with Alzheimers, a faulty blood-brain barrier prevents glucose from reaching the brain and prevents the clearing away of toxic beta-amyloid and tau proteins. This results in inflammation, which adds to vascular problems in the brain. Because it appears that Alzheimers is both a cause and consequence of vascular problems in the brain, researchers are seeking interventions to disrupt this complicated and destructive cycle.

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    What Causes Alzheimers Disease

    In recent years, scientists have made tremendous progress in better understanding Alzheimers and the momentum continues to grow. Still, scientists dont yet fully understand what causes Alzheimers disease in most people. In people with early-onset Alzheimers, a genetic mutation may be the cause. Late-onset Alzheimers arises from a complex series of brain changes that may occur over decades. The causes probably include a combination of genetic, environmental, and lifestyle factors. The importance of any one of these factors in increasing or decreasing the risk of developing Alzheimers may differ from person to person.

    Medications To Maintain Mental Function In Alzheimer’s Disease

    Several medications are approved by the U.S. Food and Drug Administration to treat symptoms of Alzheimers. Donepezil, rivastigmine, and galantamine are used to treat the symptoms of mild to moderate Alzheimers. Donepezil, memantine, the rivastigmine patch, and a combination medication of memantine and donepezil are used to treat moderate to severe Alzheimers symptoms. All of these drugs work by regulating neurotransmitters, the chemicals that transmit messages between neurons. They may help reduce symptoms and help with certain behavioral problems. However, these drugs dont change the underlying disease process. They are effective for some but not all people and may help only for a limited time.

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    Common Forms Of Dementia

    There are many different forms of dementia. Alzheimer’s disease is the most common form and may contribute to 60-70% of cases. Other major forms include vascular dementia, dementia with Lewy bodies , and a group of diseases that contribute to frontotemporal dementia . Dementia may also develop after a stroke or in the context of certain infections such as HIV, harmful use of alcohol, repetitive physical injuries to the brain or nutritional deficiencies. The boundaries between different forms of dementia are indistinct and mixed forms often co-exist.

    Early Onset Alzheimers Disease

    How Does Dementia Affect The Brain?

    Although age is the main risk factor for Alzheimers disease, this is not just a condition that affects older adults.

    According to the Alzheimers Association, early onset Alzheimers disease affects around 200,000 U.S. adults under the age of 65 years. Many people with this condition are in their 40s or 50s.

    In many cases, doctors do not know why younger people develop this condition. Several rare genes can cause the condition. When there is a genetic cause, it is known as familial Alzheimers disease.

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    Does Alzheimers Disease Reduce Life Expectancy

    Progression rate through the stage of Alzheimers disease The progression rate of Alzheimers disease varies greatly. On average, people with Alzheimers disease live between 3 and 11 years after diagnosis, but some survive for more than 20 years. The degree of disability at diagnosis can affect life expectancy.

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